Everything You Need to Know about PDO Threads

What are PDO Threads?

PDO Mono threads are becoming increasingly popular in the skin and aesthetics industry, to improve skin health and laxity.

In this month’s blog post, we are answering some of your burning questions surrounding PDO threads and what to expect.


Firstly, what are Matrix PDO Mono Threads and how do they work?

They are tiny threads made of Polydioxanone (PDO). A compound that has been used as an internal dissolvable sutures for over 50 years. The threads are laid into the skin, in a mesh-like pattern [1] by a qualified cosmetic injector, who will insert multiple small cannulas containing the threads into the area of concern.

Natural collagen production takes place around the threads over time and the skin and dermis thickens as the threads are fully absorbed by the body [2]. The treated area ends up with a meshwork of new collagen. Resulting in the skin looking fresh, volumised and rejuvenated.


How long until I start to notice results?

Skin changes will show at about week 12 and they may improve over the next 6 months. You will continue to produce new collagen for up to 12 months.

Multiple treatments may be needed.


Are they safe?

Matrix PDO Mono Threads are incredibly safe and are featured in multiple industry journals, backing their efficacy.

Interestingly, PDO threads (Lift) have been proven to improve face symmetry in those with facial palsy [3].


Does the treatment hurt?

A strong topical local anaesthetic is applied prior to treatment so there is minimal discomfort experienced.


Will I feel the Matrix PDO Mono Threads? And what is the downtime?

Thankfully, you won’t feel the threads after treatment, however there will be some extensive bruising and swelling which indicates an endpoint has been achieved.


What areas can be treated?

  • Upper and lower cheeks
  • Forehead and brow
  • Neck and jawline
  • Nose to mouth lines
  • Marionette lines
  • Decolletage
  • Arms, Buttocks
  • Abdomen


Is there anything I need to avoid after PDO threads?

24 hours after the treatment you must avoid oil based makeup and retinol.
The following 3 weeks after your treatment you will need to avoid facial massage, exercise, exaggerated face movements and saunas.

The following 4 weeks after your treatment, we also recommend that you avoid dental work.
Laser treatments are also contraindicated following PDO treatments for 6 weeks. However enhancing your skincare routine with collagen stimulating actives can aid with improving results.


What is the process for having PDO Threads at Flawless Rejuventaion Clinic in Melbourne?

Initially, a consultation occurs with one of our experienced injectors to assess for suitability and discuss downtime and recovery.

On the day of the Matrix PDO Mono Threads we do initial photography and complete consent forms and answer any remaining questions you may have.

A strong topical local anaesthetic is applied to your skin for 30 minutes prior to the PDO threads. The treatment typically takes about 30 minutes depending on the size of the area being treated.



[1] [1] Kim, B., Oh, S., & Jung, W. (2019). Understanding PDO. In The Art and Science of Thread Lifting (pp. 69-70). Springer, Singapore. https://link.springer.com/content/pdf/10.1007/978-981-13-0614-3.pdf

[2] Yoon, J. H., Kim, S. S., Oh, S. M., Kim, B. C., & Jung, W. (2019). Tissue changes over time after polydioxanone thread insertion: an animal study with pigs. Journal of cosmetic dermatology, 18(3), 885-891. https://doi.org/10.1111/jocd.12718

[3] Bhatnagar, A., Rai, R., Kumar, S., Mitra, B., Chopra, A., Singh, G. K., … & Sandhu, S. (2022). Safety and Efficacy of Restoring Facial Symmetry Using Polydioxanone Thread Face Lift Technique in Patients with Facial Palsy. The Journal of Clinical and Aesthetic Dermatology, 15(2), 26. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884188/